Salofalk 500 mg 20 tablets

Tradename:

Salofalk

Salofalk

Composition:

Each tablet contains:

Mesalazine 500 mg

Properties:

Mesalazine inhibits the activity of neutrophilic lipoxygenase and the synthesis of arachidonic acid metabolites (prostaglandins and leukotrienes), which are inflammatory mediators. It inhibits migration, degranulation, phagocytosis of neutrophils, as well as the secretion of immunoglobulins by lymphocytes. Mesalazine has antioxidant properties by binding to free oxygen radicals.

Indications:

Ulcerative colitis (treatment of exacerbations and maintenance therapy in remission); Crohn’s disease (mild and moderate forms in the acute phase); rheumatoid arthritis; juvenile rheumatoid arthritis.

Method of administration and dosage:

Take 1 tablet 3 times a day after meals.

Contraindications:

Porphyria, anemia, severe liver dysfunction, severe renal dysfunction, deficiency of the enzyme glucose-6-phosphate dehydrogenase, children under 5 years of age, lactation period; hypersensitivity to sulfonamides and salicylic acid derivatives.

Precautions:

Use with caution in patients with impaired liver and / or kidney function, patients with bronchial asthma, allergic reactions.

During the treatment period, it is recommended to consume an increased amount of liquid.

During the period of treatment, the level of liver enzymes, complete blood count and urine analysis should be monitored.

Side effects:

From the nervous system: headache, dizziness, tinnitus, ataxia, convulsions, sleep disturbances, hallucinations, peripheral neuropathy.

From the urinary system: renal dysfunction, interstitial nephritis.

From the digestive system: nausea, vomiting, diarrhea, abdominal pain, anorexia, hepatitis, pancreatitis.

From the respiratory system: interstitial pneumonitis and other lesions of the lung tissue.

From the hematopoietic system: anemia, leukopenia, thrombocytopenia, agranulocytosis.

Reproductive system disorders: transient oligospermia, infertility.

Allergic reactions: skin rash, toxic epidermal necrolysis, malignant exudative erythema, fever, anaphylactic shock.

Others: it is possible to stain yellow skin, urine, soft contact lenses.

Storage method:

At a temperature not higher than 30 degrees.

Packaging:

The cardboard box holds 20 tablets.