Tradename:

Azgovants

Azgovanc

Composition:

Each capsule contains:

Omeprazole 40 mg

Sodium bicarbonate 1100 mg

Auxiliary components:

Aerosil 200, magnesium stearate and croscarmellos sodium

Properties:

H + -K + -ATPase inhibitor. It inhibits the activity of H + -K + -ATP-ase in the parietal cells of the stomach and thereby blocks the final stage of the secretion of hydrochloric acid. This leads to a decrease in the level of basal and stimulated secretion, regardless of the nature of the stimulus. Due to a decrease in acid secretion, it reduces or normalizes the effect of acid on the esophagus in patients with reflux esophagitis.

Omeprazole has a bactericidal effect on

Helicobacter pylori. The eradication of H. pylori with the simultaneous use of omeprazole and antibiotics allows you to quickly stop the symptoms of the disease, achieve a high degree of healing of the damaged mucosa and persistent long-term remission, and reduce the likelihood of bleeding from the gastrointestinal tract.

Indications:

Peptic ulcer and duodenal ulcer in the acute phase (including associated with Helicobacter pylori), reflux esophagitis, Zollinger-Ellison syndrome, erosive and ulcerative lesions of the stomach and duodenum associated with NSAID intake.

Method of administration and dosage:

For adults

20 mg or 40 mg 1-2 times a day, depending on the disease. Take in the morning on an empty stomach, wash down with water. … The duration of treatment is 2-8 weeks.

Contraindications:

Chronic liver disease (including history), childhood, hypersensitivity to omeprazole.

Precautions:

Before starting therapy, it is necessary to exclude the possibility of a malignant process (especially with a stomach ulcer), because treatment with omeprazole can mask symptoms and delay correct diagnosis.

Against the background of the use of omeprazole, it is possible to distort the results of laboratory tests of liver function and indicators of the concentration of gastrin in the blood plasma.

Side effects:

From the digestive system: rarely – nausea, diarrhea, constipation, abdominal pain, flatulence.

From the side of the central nervous system: rarely – headache, dizziness, weakness.

From the hematopoietic system: in some cases – anemia, eosinopenia, neutropenia, thrombocytopenia.

From the urinary system: in some cases hematuria, proteinuria.

From the musculoskeletal system: in some cases – arthralgia, muscle weakness, myalgia.

Allergic reactions: rarely – skin rash.

Storage method:

In a cool dry place not higher than 30 degrees.

Packaging:

Cardboard box holds a plastic jar with 7 or 14 capsules