Ganaton 50 mg 30 tablets

Ganaton

Each tablet contains:

Itoprid hydrochloride 50 mg.

Auxiliary components:

Lactose, starch, carmellose, magnesium stearate, macrogol, titanium dioxide.

Itoprid hydrochloride is a gastroprokinetic drug for oral administration. The dosage form and composition of the tablets provide an immediate release of the active substance. Itopride is characterized by a dual mechanism of action: antagonism to D2-dopamine receptors and inhibition of acetylcholinesterase. As a result of the action of itopride, the concentration of acetylcholine increases, which leads to increased gastric motility, increased tone of the lower esophageal sphincter (LES), accelerated gastric emptying and improved gastroduodenal coordination.

Itopride hydrochloride also has an antiemetic effect by interacting with D2-dopamine receptors located in the chemoreceptor trigger zone of the medulla oblongata. Itopride causes dose-dependent suppression of apomorphine-induced vomiting.

Treating gastrointestinal symptoms associated with impaired gastric motility or delayed gastric emptying, such as:

bloating;

-fast saturation;

– a feeling of fullness in the stomach after eating;

– pain or discomfort in the epigastric region;

-decreased appetite;

-heartburn;

-nausea;

-vomit;

-Functional (non-ulcer) dyspepsia or chronic gastritis.

Adults are prescribed inside 1 tab. (50 mg) 3 times / day before meals. The recommended daily dose is 150 mg. The indicated dose can be reduced taking into account the age and symptoms of the patient.

In clinical studies, the duration of treatment with Ganaton was up to 8 weeks.

– gastrointestinal bleeding, mechanical obstruction or perforation of the gastrointestinal tract;

-pregnancy;

-period of lactation (breastfeeding);

-Children up to 16 years old (due to the lack of safety data);

-increased sensitivity to itopride or any auxiliary component of the drug.

Itopride enhances the action of acetylcholine and can cause cholinergic side reactions.

There are no data on long-term use of the drug.

From the gastrointestinal tract: often – abdominal pain, diarrhea; infrequently – increased salivation.

Laboratory and instrumental data: infrequently – an increase in ALT activity, a decrease in the number of leukocytes.

Skin and subcutaneous tissue disorders: infrequently – rash.

On the part of the blood and lymphatic system: leukopenia and thrombocytopenia.

From the immune system: hypersensitivity reactions, including anaphylactoid reaction.

From the endocrine system: an increase in the level of prolactin in the blood.

From the nervous system: dizziness, headache, tremors.

From the gastrointestinal tract: diarrhea, constipation, abdominal pain, increased salivation and nausea.

On the part of the skin and subcutaneous tissues: rash, erythema and itching.

Store at a temperature not exceeding 30 degrees.

The cardboard box contains 3 blisters of 10 tablets and paper instructions