Trade name:
Silden
Composition:
Each tablet contains:
Sildenafil 25 mg
Auxiliary components:
lactose monohydrate (milk sugar), microcrystalline cellulose, croscarmellose sodium, povidone K 25, magnesium stearate.
Properties:
Selective inhibitor of cycloguanosine monophosphate (cGMP) -specific PDE5. PDE5, responsible for the breakdown of cGMP, is contained not only in the cavernous body of the penis, but also in the vessels of the lungs.
Restores impaired erectile function and provides a natural response to sexual arousal. Sildenafil does not have a direct relaxing effect on the corpora cavernosa, but actively enhances the relaxing effect of nitric oxide on this tissue. With sexual arousal, the local release of NO under the influence of silden leads to inhibition of PDE5 and an increase In the level of cGMP in the corpus cavernosum,
resulting in relaxation of smooth muscles and increased blood flow in the corpus cavernosum.
Indications:
Treatment of erectile dysfunction characterized by the inability to achieve or maintain an erection of the penis sufficient for satisfactory intercourse.
Pulmonary hypertension.
Method of administration and dosage:
The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.
Treatment of erectile dysfunction: taken orally approximately 1 hour before the planned sexual activity. A single dose is 50 mg. Taking into account the efficacy and tolerability, the dose can be increased to 100 mg or reduced to 25 mg. The maximum single dose is 100 m
The maximum frequency of use is 1 time /
For elderly patients over the age of 65 and
with concomitant renal or hepatic impairment, the dose is 25 mg.
Contraindications:
Simultaneous intake of nitric oxide or nitrate donors in any form, hypersensitivity to sildenafil.
Precautions:
Before starting to take sildenafil for the treatment of erectile dysfunction, a cardiovascular examination should be performed.
Use with caution in patients with a tendency to bleeding, with gastric ulcer and duodenal ulcer in the acute phase, with hereditary retinitis pigmentosa.
Sildenafil is not used in patients under the age of 18.
Side effects:
From the side of the central nervous syste headache, hot flashes, dizziness, insomnia possible.
from the digestive system: possible dyspepsia, asthenia, diarrhea, abdominal pain, nausea.
Storage:
n a cool dry place at a temperature not exceeding 30 degrees.
Packaging:
The cardboard box contains 1 blister of 10 tablets, paper instructions.