Tradename:
Deposit B12
Depovit B12
Composition:
Each 1 ml ampoule contains:
Hydroxocobalamin acetate 1.04mg
Auxiliary components:
Sodium dihydrogen phosphate, water for
injection.
Properties:
It belongs to the group of water-soluble vitamins. It is a metabolite of cyanocobalamin. In contrast, in the hydroxocobalamin molecule, the cobalt atom is linked not to cyano, but to the hydroxy group. It is necessary for the process of hematopoiesis, the formation of epithelial cells, the functioning of the nervous system (due to the effect on myelin synthesis).
In the body, it turns into an active coenzyme form faster than cyanocobalamin. It remains in the blood longer, because more strongly binds to plasma proteins and is more slowly excreted in the urine.
Indications:
B12-deficiency anemia, Leber’s disease (hereditary atrophy of the optic nerves), Addison’s pernicious anemia.
Method of administration and dosage:
- ampoule intramuscularly every other day for
1-2 weeks, then for support, 1 ampoule every
3 months
Contraindications:
Hypersensitivity to hydroxocobalamin.
Precautions:
Before starting therapy, the diagnosis should be verified. the use of hydroxocobalamin at a dose of more than 10 mcg / day can cause a hematological response in patients with folic acid deficiency. Inappropriate use of hydroxocobalamin can mask the true diagnosis.
Side effects:
Rarely: allergic reactions (itching, exanthema, anaphylactic reactions), nausea, dizziness, arrhythmia (possible at the beginning of treatment).
Storage method:
At a temperature not higher than 30 degrees.
Packaging:
The cardboard box holds 2,3 or 5 ampoules of 1 ml.