Muco SR 75 mg 20 capsules

Tradename:

Muco SR

Composition:

Each capsule contains:

Ambroxol hydrochloride 75 mg

Auxiliary components:

Sucrose, starch, povidone, talc, gelatin, titanium dioxide.

Properties:

Mucolytic and expectorant agent, is an active N-demethylated metabolite of bromhexine. It has a secretory, secretolytic and expectorant effect. Stimulates serous cells of the bronchial mucosa, increases the motor activity of the ciliated epithelium by acting on type 2 pneumocytes in the alveoli and Clara cells in the bronchioles, enhances the formation of endogenous surfactant – a surfactant that ensures the sliding of bronchial secretions in the airway lumen.

Ambroxol increases the proportion of the serous component in the bronchial secretion, improving its structure and helping to redu the viscosity and thinning of sputum; as a result of this, mucociliary transport is improved

and the excretion of sputum from the bronchial tree is facilitated.

When ambroxol is taken orally, the effect, on average, occurs after 30 minutes and lasts 612 hours, depending on the single dose.

Indications:

Diseases of the respiratory tract, accompanied by the release of viscous sputum and difficulty in sputum discharge: acute and chronic bronchitis; pneumonia; bronchial asthma; bronchiectasis; COPD.

Method of administration and dosage:

Adults and children over 12 years old: 75 mg 1 time / day.

Contraindications:

Hypersensitivity to ambroxol or auxiliary components of drugs; I trimester of pregnancy; lactation period (breastfeeding); congenital fructose intolerance (for dosage forms containing fructose); up to 12 years (for extended-release capsules).

With care: impaired bronchial motility and increased mucus secretion (for example, in the rare syndrome of motionless cilia); renal impairment and / or severe hepatic impairment; peptic ulcer and duodenal ulcer (including history); Il and Ill trimesters of pregnancy; children under 2 years of age (oral solution; only as prescribed by a doctor).

Precautions:

Ambroxol should not be taken concomitantly with antitussive drugs that can inhibit the cough reflex, such as codeine. this can make it difficult to remove the liquefied phlegm from the bronchi.

Ambroxol should be used with caution in patients with a weakened cough reflex or impaired mucociliary transport due to the possibility of sputum accumulation.

Patients taking ambroxol are not recommended to perform breathing exercises due to difficulty in sputum discharge. In critically ill patients, aspiration of liquefied sputum should be performed.

You should not take Ambroxol just before bed.

In patients with bronchial asthma, ambroxol may aggravate the cough.

Patients with severe skin lesions – StevensJohnson syndrome or toxic epidermal necrolysis – may experience a flu-like condition in the early phase: fever, body pains, rhinitis, cough, pharyngitis. With symptomatic therapy, it is possible that mucolytic agents such as ambroxol hydrochloride are misused.

Side effects:

Allergic reactions: rarely – skin rash, urticaria, exanthema, facial edema, shortness of breath, itching, fever; frequency unknown anaphylactic reactions, including anaphylactic shock, angioedema, pruritus, allergic contact dermatitis.

From the digestive system: often – nausea; infrequently – vomiting, diarrhea, dyspepsia, abdominal pain.

From the nervous system: often – dysgeusia.

On the part of the skin and subcutaneous tissues: very rarely – toxic epidermal necrolysis

(Lyell’s syndrome), Stevens-Johnson syndrome; frequency unknown – acute generalized eczematous pustulosis.

From the respiratory system: often – decreased sensitivity in the mouth or pharynx; rarely dryness of the mucous membrane of the respiratory tract, rhinorrhea; in isolated cases dryness of the pharyngeal mucosa.

Storage method:

At a temperature not higher than 30 degrees. In a dry place.

Packaging:

The cardboard box holds 20 capsules.