Megafen N 100 mg / 5 ml suspension 120 ml

Tradename:

Megafen N

Megafen N

Composition:

Each 5 ml of suspension contains:

Ibuprofen 100mg

Auxiliary components:

Sucrose, methylparaben, propylparaben, sodium benzoate, kaolin, citric acid anhydride, sodium dihydrate, emulsion of simethicone 30%, agar, sorbitol solution 70% polysorbate 80, vanillin, orange oil, aerosil 200, purified water.

Properties:

NSAlDs. It has antipyretic, analgesic and antiinflammatory effects.

The antipyretic effect is due to the blocking of COX-I and COX-2 in the arachidonic acid cascade of the central nervous system, which leads to a decrease in the synthesis of prostaglandins, a decrease in their concentration in the cerebrospinal fluid and to a decrease in the excitation of the thermoregulation center. The effect of lowering the temperature with fever begins 30 minutes after taking the drug, its maximum effect is manifested after 3 hours.

Indications:

The drug is intended only for the treatment of children.

Increased body temperature of various origins with:

colds;

ARVI, incl. flu;

angina (tonsillitis);

childhood infections;

post-vaccination reactions.

Pain syndrome of various origins of mild and moderate intensity with:

toothache, painful teething;

ear pain with inflammation of the middle ear;

headache, migraine;

neuralgia;

pain in muscles, joints due to injuries of the musculoskeletal system.

It is intended for symptomatic therapy, reducing pain and inflammation during the period of use, does not affect the progression of the disease.

Method of administration and dosage:

The drug is taken orally, after meals. Before use, the bottle should be shaken until a homogeneous suspension is obtained.

Children 3-6 months: 2.5 ml 3 times a day.

Children 6-12 months: 2.5 ml 3 times a day.

Children 1-2 years old: 2.5ml 3-4 times a day.

Children 3-7 years old: 5 ml 3-4 times a day.

Children 8-12 years old: 10ml 3-4 times a day.

Taking the drug in a single dose can be repeated every 6-8 hours. Do not exceed the maximum daily dose.

Contraindications:

hypersensitivity to ibuprofen or other NSAlDs (including acetylsalicylic acid), as well as to the auxiliary components of the drug;

• severe liver failure, active liver disease;

-confirmed hyperkalemia;

-inflammatory bowel disease;

• sucrase / isomaltase deficiency;
• fructose intolerance, glucose-galactose malabsorption;
• blood clotting disorders (including hemophilia, prolongation of bleeding time, tendency to bleeding, hemorrhagic diathesis);

-Children up to 3 months.

Precautions:

In patients with bronchial asthma or other diseases associated with bronchospasm, ibuprofen may increase the risk of developing

bronchospasm. The use of the drug in these patients is permissible only if great care is taken, and in case of breathing difficulties, you should immediately consult a doctor.

During long-term treatment with NSAlDs, it is necessary to monitor the picture of peripheral blood and the functional state of the liver and kidneys.

Side effects:

From the digestive system: NSAlDsgastropathy (nausea, vomiting, loss of appetite, heartburn, abdominal pain, diarrhea, flatulence, pain and discomfort in the epigastric region); ulceration of the mucous membrane of the gums and mucous membrane of the gastrointestinal tract (in some cases complicated by perforation and bleeding); dryness of the oral mucosa, aphthous stomatitis, pancreatitis, constipation, hepatitis.

From the respiratory system: shortness of breath, bronchospasm.

From the urinary system: acute renal failure, polyuria, cystitis.

Allergic reactions: pruritus, skin rash (erythematous or urticaria), angioedema, anaphylactoid reactions, anaphylactic shock, bronchospasm, fever, exudative erythema multiforme (including Stevens-Johnson syndrome), toxic epidermal syndrome, Lewis non-corporeal eosinophilia, allergic rhinitis.

Storage method:

In a cool dry place at a temperature not exceeding 30 degrees.

Packaging:

The cardboard box holds a 60 or 120 ml bottle.