Itomash 50 mg

Trade Name:

Itomash 50 mg 

Composition:

Itopride hydrochloride 50 mg

Inactive ingredients:

Hydroxypropyl Methyl cellulose

Hydroxyethyl cellulose

Properties:

Itopride hydrochloride activates gastrointestinal propulsive motility due to its dopamine D2 antagonizing activity and acetylcholinesterase inhibitory activity. Itopride   hydrochloride activates acetylcholine release and inhibits its degradation.

Indication:

Itopride hydrochloride is used in the treatment of gastrointestinal symptoms of:

-Functional dyspepsia

-Non-ulcer dyspepsia (chronic gastritis) :

-sensation of bloating 

-early satiety

-upper abdominal pain or discomfort

-anorexia

-heartburn

-nausea and vomiting

Dosage and administration:

The recommended dose of Itomash for adult patients is 150 mg  daily (one tablet 50 mg taken three times a day before meals). The dose may be reduced according to a patient’s age and symptoms.

Contraindication:

Itopride hydrochloride is contraindicated in patients with known hypersensitivity to itopride hydrochloride or any of the excipients. It should not be used in patients in whom an increase in gastrointestinal motility could be harmful e.g. hemorrhage, mechanical obstruction or perforation.

Side effects:

• Blood and lymphatic system disorders:

Leucopenia, thrombocytopenia

• Immune system disorders:

Anaphylactoid reactions

• Endocrine disorders:

Increased prolactin level and gynecomastia

• Nervous system disorders:

Dizziness, headache and tremor

• Gastrointestinal disorders:

Diarrhea, constipation, abdominal pain, increased saliva and nausea

• Hepato-biliary disorders:

Jaundice

• Skin and subcutaneous tissue disorders:

Rash, redness and itching

Warnings and precautions:

Itomash enhances the action of acetylcholine and may produce cholinergic side effects.

Storage:

Store at a temperature not exceeding 30°C in a dry place.

Package:

The carton box holds 3 strips each of 10 tablets and inner leaflet.