Histazine‑1 Syrup 5 mg 100 ml
Composition:
Cetirizine dihydrochloride BP — 5 mg
Propylene glycol BP — 500 mg
Glycerin BP — 1000 mg
Methyl hydroxybenzoate BP — 9 mg
Propyl hydroxybenzoate BP — 1 mg
Glacial acetic acid BP — 0.005 ml
Sodium acetate (anhydrous) USP — 8 mg
Sucrose BP — 2000 mg
Coloring agent Sunset Yellow Supra IH — 10 mg
Flavoring agent Sweet Orange IH — 0.2 mg
Purified water BP — q.s.
Product description:
Second‑generation antihistamine.
Selective H1‑receptor antagonist, reduces the severity of allergic reactions, relieves itching, swelling, and inflammation.
Does not cause significant sedative effects at therapeutic doses.
Indications for use:
Seasonal and perennial allergic rhinitis (sneezing, rhinorrhea, itching, tearing).
Allergic conjunctivitis.
Urticaria (including chronic idiopathic).
Atopic dermatitis and other allergic dermatoses.
Method of Administration and dosage:
Adults and children over 12 years: 10 mg (10 ml syrup) once daily.
Children 6–11 years: 5 ml twice daily or 10 ml once daily.
Children 2–5 years: 5 mg (5 ml) once daily or 2.5 ml twice daily.
Children under 2 years: not recommended.
In case of impaired renal or hepatic function — reduce the dose by half.
Contraindications:
Hypersensitivity to cetirizine, hydroxyzine, or excipients.
Severe hepatic or renal impairment.
Children under 2 years of age.
Precautions:
Individual drowsiness may occur, especially when combined with alcohol or sedatives.
Use with caution in elderly patients and in chronic liver/kidney diseases.
Adverse reaction / Side effects:
Most common: dry mouth, drowsiness, headache, fatigue.
Less common: abdominal pain, diarrhea, skin rash.
Pregnancy and lactation:
Use during pregnancy only if prescribed by a physician when the expected benefit outweighs potential risk.
Breastfeeding should be discontinued during treatment.
Storage conditions:
Store at a temperature not exceeding 25 °C, in a dry place, protected from light.
Keep out of reach of children.
Packaging:
100 ml syrup bottle with measuring cup, packed in a carton box.