Flu C 6 sachets
Composition
Each 3 g sachet contains:
Paracetamol 500 mg
Ascorbic acid 500 mg
Caffeine anhydrous 30 mg
Chlorphenamine maleate 4 mg
Excipients: sucrose, sorbitol, flavouring agents, anticaking agents.
Description
Flu-C sachets are a fixed-dose combination powder for oral solution designed for the symptomatic treatment of common cold. Each sachet contains paracetamol for pain relief and fever reduction, ascorbic acid to support the immune system, caffeine for mental alertness, and chlorphenamine maleate to relieve allergy-related symptoms such as a runny nose and dry cough.
Properties
Flu‑C combines four actives in one sachet for rapid, multi‑symptom relief of the common cold:
-Paracetamol — central analgesic and antipyretic (inhibits COX‑1/2 in CNS)
-Ascorbic acid — antioxidant; supports immune function
-Caffeine — CNS stimulant; counteracts paracetamol‑induced drowsiness and enhances analgesia
-Chlorphenamine maleate — first‑generation antihistamine; relieves sneezing, rhinorrhoea, dry cough
Indications
Symptomatic relief in adults of:
Headache
Limb and muscle pain
Nasal congestion (“sniffles”)
Dry, irritating cough
Fever or elevated body temperature
Dosage & Administration
Adults (≥18 y): Dissolve 1 sachet in a glass of water, wait ~1 minute, then drink.
Frequency: 1 sachet every 6–8 hours, up to 3 times/day
Maximum: 4 sachets in 24 hours
Liver/renal impairment or Gilbert’s syndrome: Reduce dose or extend interval
Severe renal insufficiency: Contraindicated
Duration: Do not exceed 3 days of continuous use without medical advice
Contraindications
Hypersensitivity to any active or excipient
Severe renal impairment (eGFR <30 mL/min/1.73 m²)
Children and adolescents <18 years
Gilbert’s syndrome (risk of paracetamol accumulation)
Concurrent MAOI therapy
Precautions
Use with caution or consult a physician if the patient has:
Hepatic dysfunction or history of liver disease
Renal dysfunction
Gilbert’s syndrome
Oxalate urolithiasis (risk of oxalate stones from high-dose vitamin C)
Iron-storage disorders (thalassemia, hemochromatosis)
Chronic alcohol abuse
Pyloroduodenal or bladder‑neck obstruction
Narrow‑angle glaucoma
Gastric or duodenal ulcer
Hyperthyroidism
Cardiac arrhythmias (risk of tachycardia, extrasystoles)
Anxiety disorders (risk of exacerbation by caffeine)
General warning: Prolonged high‑dose or unsupervised use of analgesics can trigger medication‑overuse headache. Seek medical advice if symptoms worsen or persist, or if high fever or secondary infection develops.
Side Effects
-Blood & lymphatic (very rare): leukopenia, neutropenia, agranulocytosis, thrombocytopenia, pancytopenia, aplastic anemia
-Immune system (very rare): anaphylaxis, angioedema, serum‑sickness‑like reactions, hypersensitivity vasculitis; Stevens–Johnson syndrome, toxic epidermal necrolysis
-Metabolism & nutrition (very rare): increased appetite
-Psychiatric (very rare): psychotic reactions, restlessness, insomnia
-Nervous system (very rare): dyskinesias; possible sedation or drowsiness from chlorphenamine
-Eye (very rare): acute angle‑closure glaucoma, visual disturbances
-Cardiac (unknown): tachycardia, palpitations
-Respiratory (very rare): bronchospasm (analgesic‑induced asthma)
-Gastrointestinal
Common: dry mouth
Very rare: nausea, vomiting, diarrhea, abdominal pain
-Hepatobiliary
Rare: elevated liver enzymes
Very rare: severe liver injury with prolonged overdose
-Skin & subcutaneous
Uncommon: rash, urticaria, pruritus
Very rare: severe bullous reactions
-Renal & urinary (very rare): urinary retention; chronic high‑dose use may damage kidneys
-Laboratory (unknown): interference with tests for glucose, uric acid, creatinine, occult blood, etc.
Pregnancy & Lactation
Pregnancy: Contraindicated. Chlorphenamine has been linked to fetal CNS/cranial anomalies; vitamin C at very high doses may harm.
Breast‑feeding: Contraindicated. Chlorphenamine excretion into milk unknown; may cause sedation in infant.
Storage
Store in the original carton at a temperature ≤ 30 °C, in a dry place. Protect from moisture and light. Keep out of reach of children.
Packaging
Carton box containing 6 sachets plus package leaflet.