Dalacin 2% vaginal cream

Trade Name:

Dalacin 2% vaginal cream

16,5 gm with 3 applicators

Composition:

Each gram of cream contains:

Clindamycin phosphate 20 mg 

Inactive ingredients: 

Benzyl alcohol (E1519), sorbitan stearate, polysorbate 60, propylene glycol (E1520), stearic acid, cetostearyl alcohol, cetyl palmitate, liquid paraffin, water 

Properties:

Clindamycin is an antibiotic that belongs to the group of lincosamides. Clindamycin phosphate binds to bacterial ribosomal proteins by competitive inhibition and blocks protein synthesis, leading to cell death.

Indications:

Treatment of bacterial vaginosis 

Directions for use:

-Always use this medicine exactly as your doctor has told you..

-The usual dose is one applicator full (approx 5 grams), which should be placed into the vagina each night at bedtime for seven consecutive nights. 

-Always wash your hands before using the cream.

-Remove the cap from the tube. 

Screw one of the disposable plastic applicators supplied on to the tube where the cap has been  removed. Holding the tube from the bottom, squeeze gently and force the cream into the applicator. When the plunger stops moving, the applicator is full. 

Unscrew the applicator and replace the cap on the tube.

-Lie on your back, firmly grasp the applicator barrel, and insert gently into the vagina as far as possible without causing discomfort. Still holding the barrel, slowly push the plunger until it stops and all the cream has been expelled. 

-Carefully withdraw the applicator and dispose of it. It is preferable to wrap it in paper before  disposal in a waste container. Do not try to flush it down the toilet. 

-Wash your hands well after applying the cream.

-If you use more Dalacin Cream than you should, if you missed the dose or if you swallow Dalacin Cream, contact your doctor.

-Even if you do feel better, do not 

stop using the cream until you have completed the full course of treatment.

Side effects:

Very common:

• Vaginal thrush

Common:

• Fungal infection (candida), can cause red, itchy rashes
• Headache, dizziness
• Change to sense of taste
• Cough, cold, sore throat
• Stomach-ache
• Difficulty or delay emptying bowels
• Diarrhoea
• Feeling sick (nausea)
• Vomiting
• Itchy skin
• Rash
• Back pain
• Urinary tract infection
• Increased levels of sugar and protein in the urine 
• Abnormal labour
• Vaginal pain and swelling
• Abnormal bleeding, pain,menstrual disorder
• Vaginal discharge

Uncommon:

• Bacterial infection
• A sensation of whirling and loss of balance
• Nosebleed
• Upset stomach
• Bad breath
• Passing wind
• Reddening of the skin
• A nettle-like rash, hives
• Painful urination
• Vaginal infection
• Pelvic pain
• Abnormal laboratory test result
• Overactive thyroid gland which can cause increased appetite, weight loss or sweating
• Bowel disorder
• Pseudomembranous colitis
• Indigestion 
• Rash with red spots
• Pain in women’s lower tummy or back
• Body pain
• Swelling

Contraindications:

Do not use Dalacin Cream

• if you are allergic to clindamycin, lincomycin or any of the other ingredients of this medicine;
• if you suffer with a history of inflammatory bowel disease or antibiotic-associated colitis.

Warnings and precautions

• Talk to your doctor or pharmacist before using this medicine if you have diarrhoea or usually get diarrhoea when you take antibiotics;
• If you develop severe, prolonged or bloody diarrhoea during or after using Dalacin Cream tell your doctor immediately since it may be necessary to interrupt the treatment. This may be a sign  of bowel inflammation (pseudomembranous colitis), which can occur following treatment with antibiotics;

• As with all vaginal infections, sexual intercourse during treatment with Dalacin Cream is not recommended. Dalacin Cream may weaken condoms and diaphragms. Do not rely on condoms or contraceptive diaphragms when using this medicine;
• The use of other vaginal products such as tampons or douches (vaginal washes) during treatment with the cream is not recommended;
• Dalacin Cream is not recommended for use in children;
• Other medicines and Dalacin Cream

Tell your doctor if you are taking, have taken or might take any other medicines.

• Pregnancy and breast-feeding If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine;
• Breast-feeding

Tell your doctor if you will be breast-feeding while using Dalacin Cream as the active substance in this medicine may be passed into breast milk;

• Driving and using machines

No effects on the ability to drive or use machines have been seen with Dalacin Cream.

• Dalacin Cream contains propylene glycol, cetostearyl alcohol and benzyl alcohol.

They may cause allergic reactions and mild local irritation.

Storage:

Store at a temperature not exceeding 25ºC. Do not freeze.