Cetafen-N syrup 120 ml

Tradename:

Cetafen-N (Cetafen-N)

Compound:

Each 5 ml suspension contains:

Ibuprofen 100 mg

Auxiliary components:

Sodium carboxymethylcellulose, glycerol, sucrose, sodium benzoate, sodium citrate, disodium edetate, sodium chloride, polysorbitol 20, aerosil 200, vanilla and cherry flavors.

Properties:

NSAIDs, a derivative of phenylpropionic acid. It has anti-inflammatory, analgesic and antipyretic effects.

The mechanism of action is associated with the inhibition of the activity of COX, the main enzyme of the metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. The analgesic effect is due to both peripheral (indirectly, through the suppression of prostaglandin synthesis) and the central mechanism (inhibition of prostaglandin synthesis in the central and peripheral nervous system). Suppresses platelet aggregation.

Indications:

Symptomatic treatment as an anti-inflammatory and antipyretic.

Dosage and administration:

Taken inside. The individual dosing regimen depends on the indications, the severity of clinical manifestations, and the age of the patient.

A single dose for adults and children over 6 years of age is 200-400 mg. Can be taken 3-4 times a day.

The maximum daily dose for adults is 1200 mg; for children aged 12-17 years – 1000 mg; for children aged 6 to 12 years – 800 mg.

For children under 6 years of age, the dose depends on the age and body weight of the child. The maximum daily dose should not exceed 30 mg / kg of body weight with intervals between doses of the drug 6-8 hours.

Contraindications:

Hypersensitivity to ibuprofen;

– erosive and ulcerative lesions of the gastrointestinal tract in the acute phase or ulcer bleeding in the active phase or in history (2 or more confirmed episodes of peptic ulcer or ulcer bleeding);

– bleeding or perforation of an ulcer of the gastrointestinal tract in history, provoked by the use of NSAIDs;

– severe heart failure (functional class IV according to the NYHA classification);

– severe impairment of kidney and / or liver function;

– diseases of the optic nerve, “aspirin triad”, disorders of hematopoiesis;

– the period after coronary artery bypass grafting;

– intracranial or other bleeding;

– hemophilia and others, blood clotting disorders (including hypocoagulation), hemorrhagic diathesis;

– III trimester of pregnancy.

Precautionary measures:

It is recommended to prescribe ibuprofen for the longest possible, short course and at the lowest effective dose necessary to eliminate symptoms. If you need systemic use for more than 10 days, you should consult your doctor.

During long-term treatment, it is necessary to control the picture of peripheral blood and the functional state of the liver and kidneys. When symptoms of gastropathy appear, careful monitoring is indicated, including esophagogastroduodenoscopy, complete blood count (hemoglobin determination), fecal occult blood analysis.

Side effects:

On the part of the hematopoietic system: very rarely – hematopoietic disorders.

From the immune system: infrequently – hypersensitivity reactions – nonspecific allergic reactions and anaphylactic reactions, reactions from the respiratory tract.

From the digestive system: infrequently – abdominal pain, nausea, dyspepsia.

From the side of the liver and biliary tract: very rarely – abnormal liver function, increased activity of hepatic transaminases, hepatitis and jaundice.

Storage method:

Store at a temperature not exceeding 30 degrees.

Package:

The cardboard box contains a 120 ml plastic bottle and paper instructions.