Amaryl M 2/500mg 30 tab

Trade name:

Amaryl M

Amaryl M

Composition:

Each p / o tablet contains:

Glimepiride – 2mg.

Metformin Hydrochloride – 500mg

Auxiliary components:

lactose, sodium gluconate starch, povidone 1<30, microcrystalline cellulose, crospovidone, magnesium stearate, hydroxypropyl methylcellulose, macrogel 6000, titanium dioxide, wax.

Properties:

Amaryl M is a combination drug taken by mouth to lower blood sugar levels.

Indications:

Used with diet and exercise to treat a specific form of diabetes (type 2 diabetes mellitus): – in case glimepiride or metformin alone does not control blood glucose levels.

Mode of application:

Inside before or during meals, swallow whole with a glass of water 1 or 2 times a day, as directed by a doctor. The dose is determined individually. It is recommended to use an antidiabetic agent in the smallest dose. If you accidentally missed the next dose, in no case should you compensate with a double dose of the drug. The maximum single dose of metformin is 1000 mg, the maximum daily dose is 2000 mg. The maximum daily dose of glimepiride is 8 mg. Glimepiride doses exceeding 6 mg per day are more effective in only a small number of patients.

Diabetic ketoacidosis, diabetic coma and precoma, acute / chronic metabolic acidosis; type 1 diabetes mellitus; severe functional disorders of the liver, kidneys and renal failure, being on hemodialysis; acute and chronic lesions that can cause tissue hypoxia (shock, heart / respiratory failure, acute and subacute myocardial infarction); stressful situations (burns, severe infections with a febrile condition, severe trauma, surgery); violation of absorption of food and drugs in the gastrointestinal tract; fasting, exhaustion, adherence to a hypocaloric diet; acute alcohol intoxication; lactase deficiency, galactose

intolerance, glucose-galactose malabsorption; age up to 18 years; pregnancy and breastfeeding; hypersensitivity to any of the constituents of Amaril M.

Precautions:

In the first weeks of treatment, the risk of hypoglycemia may increase, which requires particularly careful monitoring of the blood glucose concentration. Hypoglycemia can be quickly resolved with immediate intake of rapidly absorbing carbohydrates (glucose or sucrose), but may return. In case of severe hypoglycemia, immediate treatment and medical supervision or even hospitalization are additionally required. During treatment with glimepiride, regular monitoring of liver and blood function (especially the number of leukocytes and platelets) is required.

Side effects:

Symptoms of hypoglycemia. The clinical picture of severe hypoglycemia may resemble a stroke. Symptoms of hypoglycemia almost always disappear after its elimination. A temporary change in the swelling of the len depending on the concentration of glucose In the blood, and due to this, a change in the

refractive index of the lens. Nausea, vomiting, feeling of heaviness or fullness in the epigastrium, abdominal pain, diarrhea; hepatitis, cholestasis, and jaundice, which can progress to life-threatening liver failure.

Hemolytic anemia. Itching, urticaria, skin rash. If symptoms of hives develop, you should see a doctor immediately.

Storage:

Store at a temperature not exceeding 30C, out of reach of children.

Packaging:

The cardboard box contains 1, 2 or 3 blisters of 10 tablets each, paper instructions.