Dantrelax 25 mg 30 capsules
Composition:
Active ingredient:
Dantrolene Sodium — 25 mg per capsule.
Dantrelax 25 mg is a peripherally acting muscle relaxant containing dantrolene sodium. It is used for the treatment of spastic conditions of skeletal muscles.
Pharmacological action:
Dantrolene sodium is a peripherally acting muscle relaxant. Unlike central muscle relaxants, it acts directly on skeletal muscle by inhibiting the release of calcium from the sarcoplasmic reticulum of the muscle fiber. This prevents muscle contraction and reduces muscle tone.
Indications for use:
1. Spastic conditions in neurological disorders:
- Cerebral palsy
- Multiple sclerosis
- Spinal cord injuries
- Post-stroke conditions
- Chronic spasticity of various origins.
2. Malignant hyperthermia:
- Prevention and treatment during anesthesia (especially when using trigger anesthetics such as halothane and succinylcholine).
Dosage and administration:
Adults:
- Initial dose: 25 mg once daily for 1–2 days.
If well tolerated, the dose is gradually increased:
up to 25 mg 3–4 times a day;
then up to 50 mg 3–4 times a day;
maximum dose — 100 mg 3–4 times a day.
- Maintenance dose is selected individually.
Important: treatment should be carried out under medical supervision with liver function monitoring.