Cipro 500 mg 10 tablets

Cipro 500 mg 10 tablets

Composition:

Each tablet contains:
Ciprofloxacin — 500 mg.
Excipients:
microcrystalline cellulose, polyvinylpyrrolidone, sodium croscarmellose, colloidal silicon dioxide, magnesium stearate.

Product Description:

Broad‑spectrum antimicrobial agent, fluoroquinolone derivative.
Ciprofloxacin inhibits bacterial DNA gyrase (topoisomerases II and IV), disrupting DNA synthesis, growth, and division.
It causes morphological changes in bacterial cell walls and membranes, leading to rapid cell death.
It acts bactericidally on gram‑negative organisms during resting and dividing phases, and on gram‑positive organisms only during division.

Indications for Use:

Uncomplicated and complicated infections caused by ciprofloxacin‑sensitive microorganisms.

Method of Administration and Dosage:

• Dosage regimen is individualized by the physician depending on indication, clinical situation, and patient age.
• Adults: 250–750 mg twice daily.
• Children: 15–20 mg/kg twice daily.
• Treatment duration: 7–14 days.
• Administer orally with sufficient water.

Contraindications:

• Hypersensitivity to ciprofloxacin or other fluoroquinolones.
• Concomitant use with tizanidine (risk of hypotension, drowsiness).
• Pregnancy.
• Breastfeeding.

Precautions:

Hypersensitivity reactions may occur even after the first dose; rare cases of anaphylaxis and anaphylactic shock have been reported.
Severe or prolonged diarrhea may indicate pseudomembranous colitis, requiring immediate discontinuation and appropriate therapy (e.g., oral vancomycin).
Antiperistaltic agents are contraindicated in this situation.

Adverse Reactions / Side Effects:

• Gastrointestinal: common — nausea, diarrhea; uncommon — vomiting, abdominal pain, dyspepsia, flatulence; very rare — pancreatitis.
• Children: arthropathy (arthralgia, arthritis).
• Infections: uncommon — fungal superinfections; rare — pseudomembranous colitis (very rare fatal cases).
• Hematologic: uncommon — eosinophilia.
• Allergic: uncommon — urticaria; rare — angioedema; very rare — anaphylaxis, serum sickness.
• Vision: rare — visual disturbances; very rare — color perception disorders.
• Hearing: rare — tinnitus, hearing loss; very rare — auditory impairment.

Pregnancy and Lactation:

Contraindicated during pregnancy and breastfeeding.

Storage Conditions:

Store at temperatures not exceeding 30 °C.

Packaging:

Carton box containing 10 tablets and leaflet.