Ciprofar 750 mg 10 tablets

Trade name:

Ciprofar

Ciprofar

Compound:

Each tablet contains:

Ciprofloxacin 750 mg

Auxiliary components:

Microcrystalline cellulose, starch, povidone K25, crospovidone, magnesium stearate, colloidal silicon dioxide.

Properties:

A broad-spectrum antimicrobial agent, a fluoroquinolone derivative.

Suppresses bacterial DNA gyrase (topoisomerases II and IV, responsible for the process of supercoiling of chromosomal DNA around nuclear RNA, which is necessary for reading genetic information), disrupts DNA synthesis, growth and division of bacteria; causes pronounced morphological changes (including the cell wall and membranes) and rapid death of the bacterial cell.

It acts bactericidal on gram-negative organisms during dormancy and division (because it affects not only DNA gyrase, but also causes lysis of the cell wall), on gram-positive microorganisms – only during the period of division.

Indications:

Uncomplicated and complicated infections caused by microorganisms sensitive to ciprofloxacin.

Mode of application:

The optimal dosing regimen is determined by the doctor. Compliance of the used dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.

Individual, depending on the indications, the clinical situation and the age of the patient.

Inside adults – 250-750 mg 2 times / day; children 15-20 mg / kg 2 times / day. The course of treatment is from 7 to 14 days.

Contraindications:

Hypersensitivity to ciprofloxacin or other drugs from the group of fluoroquinolones; the simultaneous use of ciprofloxacin and tizanidine due to clinically significant side effects (arterial hypotension, drowsiness) associated with an increase in the concentration of tizanidine in the blood plasma; pregnancy; breastfeeding period.

Precautionary measures:

Sometimes, after taking the first dose of ciprofloxacin, hypersensitivity reactions may develop, incl. allergic reactions. In rare cases, after the first application, anaphylactic reactions up to anaphylactic shock may occur. In these cases, the use of ciprofloxacin should be immediately discontinued and appropriate treatment should be carried out.

If severe and prolonged diarrhea occurs during or after treatment with ciprofloxacin, the diagnosis of pseudomembranous colitis should be excluded, which requires immediate discontinuation of the drug and the appointment of appropriate treatment (vancomycin orally at a dose of 250 mg 4 times / day). In this situation, the use of drugs that suppress intestinal motility is contraindicated.

Side effects:

From the digestive system: often – nausea, diarrhea; infrequently – vomiting, abdominal pain, dyspepsia, flatulence; very rarely – pancreatitis.

Children often have arthropathy. The frequency of arthropathy (arthralgia, arthritis) mentioned above is based on clinical studies in adult patients.

Infectious and parasitic diseases: infrequently – mycotic superinfections; rarely – pseudomembranous colitis (in very rare cases with a possible fatal outcome).

From the hemopoietic system: infrequently – eosinophilia.

Allergic reactions: infrequently – urticaria; rarely – allergic edema / angioedema; very rarely – anaphylactic reactions, anaphylactic shock (life-threatening), serum sickness.

On the part of the organ of vision: rarely – visual disturbances; very rarely – a violation of color perception.

On the part of the organ of hearing and labyrinth disorders: rarely – tinnitus, hearing loss; very rarely – hearing impairment.

Storage:

Store at a temperature not exceeding 30 degrees.

Package:

The cardboard box contains 10 tablets and paper instructions.

Manufacturer:

Egypt