Bon-One 0.25 mg 30 tablets
Composition:
Each tablet contains:
Alfacalcidol - 0.25 mcg.
Description:
A vitamin D preparation in the form of alfacalcidol used to correct calcium-phosphorus metabolism disorders. Effective in osteoporosis, hypoparathyroidism, osteomalacia, and other conditions associated with a deficiency of the active form of vitamin D.
Pharmacological properties:
• Pharmacological group: Vitamin D analogues (prodrug)
• Mechanism of action:
Alfacalcidol is converted in the body to calcitriol—the active form of vitamin D, which regulates:
- Absorption of calcium and phosphorus in the intestines
- Bone mineralization
- Parathyroid gland function
- Has anti-osteoporotic and calcium-regulating effects.
Indications for use:
• Chronic renal failure (CRF)
• Hypoparathyroidism
• Rickets and osteomalacia
• Osteoporosis (including postmenopausal and glucocorticoid-induced)
• Hypophosphatemic conditions.
Dosage and administration:
Typical dose for adults:
0.25 mcg once daily
If necessary — increase to 0.5–1.0 mcg/day (under medical supervision)
• Take orally, regardless of food intake
• Dose adjustment is individual, depending on calcium and phosphorus levels
• Important: regular monitoring of serum calcium (especially in patients with CRF).