Adolor 15 mg / 1 ml 3 ampoules

Adolor

Each 1 ml ampoule contains:

Ketorolac tromethamine 15 mg

Auxiliary components:

Sodium chloride, benzyl alcohol, ethyl alcohol 96%, water for injection.

Ketorolac is an NSAID that has a pronounced analgesic (analgesic) effect, also has an anti-inflammatory and moderate antipyretic effect.

The mechanism of action is associated with non-selective inhibition of the activity of the enzymes COX-1 and COX-2, mainly in peripheral tissues, which results in inhibition of the biosynthesis of prostanglandins – modulators of pain sensitivity, inflammation and thermoregulation. Ketorolac is a racemic mixture of R (+) and S (-) – enantiomers, while the analgesic (analgesic) effect is due to the S (-) – enantiomer.

Ketorolac does not affect opioid receptors, does not depress respiration, does not cause drug dependence, does not have a sedative and anxiolytic effect.

The strength of the analgesic (pain-relieving) effect is comparable to that of morphine, significantly superior to other NSAIDs.

Pain syndrome of severe and moderate severity: trauma, toothache, pain in the postoperative period, cancer, myalgia, arthralgia, neuralgia, sciatica, dislocations, sprains, rheumatic diseases.

Designed for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease.

Intravenous, intramuscular. It is injected deep into the muscle, slowly (or intravenously by jet) for at least 15 seconds in the minimum effective doses, in a minimally short course.

Doses for single parenteral administration:

Single doses for a single intramuscular or intravenous injection: adults under the age of 65 – 10-30 mg, depending on the severity of the pain syndrome; elderly patients over 65 years of age or with impaired renal function – 10-15 mg.

Doses for multiple parenteral administration:

For intramuscular administration, adults under the age of 65 and children over 16 years of age are injected intramuscularly 10-60 mg in the first administration, then 10-30 mg every 6 hours (usually 30 mg every 6 hours); elderly patients over 65 years of age or with impaired renal function – 10-15 mg every 4-6 hours.

With parenteral administration, the duration of the course of treatment should not exceed 5 days.

History of erosive and ulcerative lesions of the gastrointestinal tract, impaired renal function (serum creatinine level above 442 μmol / l), hypovolemia, dehydration, asthma, bronchospasm, blood clotting disorders, high risk of postoperative bleeding, the possibility or presence of gastrointestinal and / or craniocerebral hemorrhage and disorders of hemostasis, the period of pregnancy and lactation, age less than 16 years, increased individual sensitivity to ketorolac and other NSAIDs.

Care must be taken when prescribing the drug to patients over the age of 65, patients with impaired liver and kidney function, chronic heart failure, hypertension, asthma and broncho-obstructive syndrome, as well as during activities requiring increased attention and speed of psychomotor reactions.

From the digestive tract: dyspepsia, nausea, pain in the epigastric region, in isolated cases – flatulence, belching, vomiting, constipation, erosive and ulcerative lesions of the gastrointestinal tract, liver dysfunction.

From the side of the central nervous system: headache, dizziness, drowsiness, insomnia, depression.

From the urinary system: increased urination, oliguria, hematuria.

On the part of the blood coagulation system: the formation of hematomas, postoperative bleeding, nosebleeds, an increase in bleeding time. Allergic reactions: pruritus, urticaria, laryngeal edema, bronchospasm.

Store at a temperature not exceeding 30 degrees.

The cardboard box contains 3 ampoules of 1 ml, paper instructions.