Verdenodeb 20 mg 4 tablets

Trade Name:

Verdenodeb

Vardenafil 20 mg

4 film coated tablets

Composition:

Vardenafil 20 mg

Inactive ingredients:

Microcrystalline cellulose, magnesium stearate, crospovidone

Properties:

A drug for the treatment of erectile dysfunction, a PDE5 inhibitor.

The erection of the penis is a hemodynamic process, which is based on the relaxation of the smooth muscles of the cavernous bodies and the arterioles located in it. During sexual stimulation, nitric oxide (NO) is released from the nerve endings of the cavernous bodies, activating the enzyme guanylate cyclase, which leads to an increase in the content of cyclic guanosine monophosphate (cGMP) in the cavernous bodies. As a result, the smooth muscles of the cavernous bodies are relaxed, which contributes to an increase in blood flow to the penis.

Vardenafil blocks PDE5, under the influence of which cGMP is cleaved, as a result, the effect of endogenous NO in the cavernous bodies during sexual stimulation increases, which determines the ability of vardenafil to enhance the natural response to sexual stimulation.

Indications:

Erectile dysfunction (inability to achieve and maintain an erection necessary for sexual intercourse).

Dosage and administration:

At the beginning of treatment, the recommended dose is 10 mg. It is taken orally, if necessary, approximately 25-60 minutes before sexual intercourse. Along with this, vardenafil can also be taken at any time in the period from 4-5 hours to 25 minutes before sexual activity. The maximum recommended frequency of administration is 1 time / day.

Depending on the effectiveness and tolerability of treatment, the dose can be increased to 20 mg or reduced to 5 mg / day.

The maximum recommended dose is 20 mg 1 time / day.Contraindications:

Simultaneous therapy with nitrates or drugs that are nitric oxide donators; children and adolescents up to 18 years of age; hypersensitivity to vardenafil.

Precautionary measures:

Use with caution in patients with anatomical deformity of the penis (curvature, cavernous fibrosis or Peyronie’s disease), as well as in patients with diseases predisposing to the development of priapism (sickle cell anemia, multiple myeloma or leukemia).

Side effects:

From the nervous system: possible headache, dizziness; rarely – increased muscle tone.

From the side of the cardiovascular system: redness of the face is possible; rarely – an increase in blood pressure, a decrease in blood pressure.

From the digestive system: possible – dyspepsia, nausea.

From the respiratory system: nasal congestion is possible.

Dermatological reactions: rarely – photosensitivity.

From the reproductive system: rarely – priapism.

Storage:

Store at a temperature not exceeding 30°C.

Package:

Carton box holds 2 strips each of 2 film coated tablets and paper instructions