Tariflox 200 mg

Trade Name:

Tariflox

Composition:

Each tablet contains:

Ofloxacin 200 mg

Inactive ingredients:

Lactose monohydrate, polyvinylpyrrolidone, croscarmellose sodium, magnesium stearate, microcrystalline cellulose.

Properties:

A broad-spectrum antimicrobial drug from the group of fluoroquinolones. It acts on the bacterial enzyme DNA gyrase, which ensures supercoiling and, thus, the stability of bacterial DNA (destabilization of DNA chains leads to their death). It has a bactericidal effect.

Indications:

– infectious and inflammatory diseases of the respiratory tract (bronchitis, pneumonia);

– infectious and inflammatory diseases of the upper respiratory tract (sinusitis, pharyngitis, otitis media, laryngitis);

– infectious and inflammatory diseases of the skin and soft tissues;

– infectious and inflammatory diseases of bones and joints;

– infectious and inflammatory diseases of the abdominal cavity (including infections of the gastrointestinal tract) and biliary tract;

– infectious and inflammatory diseases of the kidneys (pyelonephritis) and urinary tract (cystitis, urethritis);

– infectious and inflammatory diseases of the pelvic organs (endometritis, salpingitis, oophoritis, cervicitis, parametritis, prostatitis) and genital organs (colpitis, orchitis, epididymitis);

-gonorrhea;

– chlamydia;

-meningitis;

– prevention of infections in patients with impaired immune status (including with neutropenia).

Dosage and administration:

Doses are selected individually depending on the location and severity of the infection, as well as the sensitivity of microorganisms, the general condition of the patient and the function of the liver and kidneys.The drug is prescribed orally for adults – 200-800 mg / day, the frequency of use – 2 times / day. The course of treatment is 7-10 days. Doses up to 400 mg/day may be given as a single dose, preferably in the morning.

In acute gonorrhea – 400 mg once.

Tablets should be taken whole with water, before or during a meal.

The duration of the course of treatment is determined by the sensitivity of the pathogen and the clinical picture; treatment should be continued for another 3 days after the disappearance of the symptoms of the disease and the complete normalization of the temperature.

In the treatment of salmonellosis, the course of treatment is 7-8 days, with uncomplicated infections of the lower urinary tract – 3-5 days.

Contraindications:

– deficiency of glucose-6-phosphate dehydrogenase;

epilepsy (including history);

-reduction of the convulsive threshold (including after a traumatic brain injury, stroke or inflammatory processes in the central nervous system);

– age up to 18 years (because the growth of the skeleton is not completed);

pregnancy;

– lactation (breastfeeding);

– Hypersensitivity to the components of the drug.

With caution, the drug should be prescribed for atherosclerosis of cerebral vessels, cerebrovascular accidents (in history), chronic renal failure, organic lesions of the central nervous system.

Warnings and precautions:

It is not the drug of choice for pneumonia caused by pneumococci. Not indicated in the treatment of acute tonsillitis.

It is not recommended to use the drug for more than 2 months. Avoid exposure to sunlight, exposure to UV rays (mercury-quartz lamps, solarium).In the event of side effects from the central nervous system, allergic reactions, pseudomembranous colitis, drug withdrawal is necessary. For pseudomembranous colitis confirmed colposcopically and/or histologically, oral administration of vancomycin and metronidazole is indicated.

Side effects:

From the digestive system: anorexia, nausea, vomiting, diarrhea, flatulence, abdominal pain (including gastralgia).

From the side of the central nervous system: headache, dizziness, uncertainty of movements, tremor, convulsions, numbness and paresthesia of the extremities.

From the musculoskeletal system: tendonitis, myalgia, arthralgia, tenosynovitis, tendon rupture.

From the side of the cardiovascular system: tachycardia, vasculitis, collapse.

On the part of the skin: pinpoint hemorrhages (petechiae), bullous hemorrhagic dermatosis.

On the part of the hematopoietic organs: leukopenia, agranulocytosis, anemia.

From the urinary system: acute interstitial nephritis, impaired renal function.

Allergic reactions: skin rash, itching, urticaria, allergic pneumonitis, allergic nephritis, eosinophilia, fever, angioedema, bronchospasm, Stevens-Johnson syndrome, Lyell’s syndrome, photosensitivity, erythema multiforme; rarely – anaphylactic shock.

Others: dysbacteriosis, superinfection, hypoglycemia (in diabetic patients), vaginitis.

Storage:

Store at a temperature not exceeding 30°C.

Package:

The carton box contains a blister of 10 tablets