Melacryst 1.5mg 20 Soluble Films

Tradename:

Melacryst (Melacryst)

Compound:

Each oral dissolvable film contains:

Melatonin 1.5 mg

Auxiliary components:

Polyvinyl alcohol, polyethylene glycol, starch, glycerol, menthol, blueberry flavor, simethicone.

Properties:

Synthetic analog of the pineal gland hormone (pineal gland) melatonin.

It has an adaptogenic, sedative, hypnotic effect.

Normalizes circadian rhythms. Increases the concentration of GABA and serotonin in the midbrain and hypothalamus, changes the activity of pyridoxalkinase involved in the synthesis of GABA, dopamine and serotonin. It is known that GABA is an inhibitory mediator in the CNS, and a decrease in the activity of serotonergic mechanisms may be important in the pathogenesis of depressive states and disorders.

It regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature, positively affects the intellectual-mnestic functions of the brain, and the emotional-personal sphere. Promotes the organization of the biological rhythm and the normalization of night sleep. Improves the quality of sleep, reduces the frequency of attacks of headaches, dizziness, improves mood. Accelerates falling asleep, reduces the frequency of nocturnal awakenings, improves well-being after morning awakening, does not cause a feeling of lethargy, weakness and fatigue upon awakening. Makes dreams more vivid and emotionally rich.

Indications:

With sleep disorders, incl. caused by a violation of the “sleep-wakefulness” rhythm, such as desynchronosis (a sharp change in time zones).

Dosage and administration:

The optimal dosing regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.

Individual. Stick the film soluble in the oral cavity on the tongue at a dose of 1.5 mg 1 time / day 30-40 minutes before bedtime.

Contraindications:

Hypersensitivity to melatonin; severe renal dysfunction (CC <30 ml / min), autoimmune diseases (no clinical data), liver failure, pregnancy, breastfeeding, age up to 18 years (efficacy and safety have not been established).

With caution: renal failure (CC> 30 ml / min), advanced age.

Precautionary measures:

During the period of melatonin use, it is recommended to avoid exposure to bright light.

It is necessary to inform women planning a pregnancy that melatonin has a weak contraceptive effect.

During the period of use of melatonin, you should not drink alcohol, which reduces its effectiveness.

Side effects:

From the hemopoietic system: rarely – leukopenia, thrombocytopenia.

From the immune system: the frequency is unknown – hypersensitivity reactions.

From the side of metabolism: rarely – hypertriglyceridemia, hypokalemia, hyponatremia.

Storage method:

Store at a temperature not exceeding 30 degrees.

Package:

The cardboard box contains 20 films, paper instructions.