Clindam 300 mg 16 capsules

Clindam 300 mg 16 capsules

Composition:

Each capsule contains Clindamycin (as clindamycin hydrochloride) — 300 mg.
The excipients are lactose monohydrate, magnesium stearate, talc, starch, gelatin, and titanium dioxide.

Product Description:

Clindam is a lincosamide antibiotic with bacteriostatic action that inhibits protein synthesis in microorganisms.
The drug exhibits a broad spectrum of activity against Gram-positive and anaerobic bacteria, including staphylococci, streptococci, clostridia, bacteroides, propionibacteria, and actinomycetes.
Compared to lincomycin, it demonstrates significantly higher antimicrobial activity against anaerobic microorganisms.

Indications for Use:

• Upper and lower respiratory tract, ear, nose, and throat infections (pharyngitis, tonsillitis, sinusitis, otitis media, pneumonia, lung abscess, pleural empyema, bronchitis), as well as scarlet fever and diphtheria.
• Urogenital tract infections (chlamydia, endometritis, vaginal infections, tubo-ovarian inflammation).
• Skin, soft tissue, abdominal, and oral cavity infections (infected wounds, abscesses, furuncles, felon, peritonitis).
• Acute and chronic osteomyelitis, septicemia, bacterial endocarditis.
• Prevention of peritonitis and intra-abdominal abscesses after intestinal perforation or trauma (in combination with aminoglycosides).

Method of Administration and Dosage:

The medication is taken orally, preferably with food, with a full glass of water to avoid esophageal irritation.
For adults, the dosage ranges from 600 mg to 1800 mg per day, divided into 2, 3, or 4 equal doses.
For children over 6 years of age, the recommended dose is 8–25 mg/kg per day, also divided into 3 or 4 equal doses.

Contraindications:

• Hypersensitivity to clindamycin, lincomycin, or any of the excipients.
• Gastrointestinal diseases (especially ulcerative colitis, regional enteritis, or antibiotic-associated colitis).
• Severe hepatic or renal impairment.
• Pregnancy and lactation.

Precautions:

The drug should be used with caution in patients with a history of bronchial asthma, gastrointestinal disorders (especially colitis), atopy, or a history of allergic reactions to medications.

Adverse Reactions / Side Effects:

• Gastrointestinal Disorders: abdominal pain, nausea, diarrhea, vomiting, esophagitis, pseudomembranous enterocolitis, dysbiosis, esophageal ulcers.
• Blood and Lymphatic System Disorders: leukopenia, neutropenia, agranulocytosis, thrombocytopenia, eosinophilia, thrombocytopenic purpura.
• Skin and Subcutaneous Tissue Disorders: papular rash, urticaria, exfoliative dermatitis, bullous dermatitis.
• Hepatobiliary Disorders: hepatotoxicity, hyperbilirubinemia, jaundice.
• Immune System Disorders: hypersensitivity reactions (angioedema, anaphylaxis), Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome.
• Musculoskeletal Disorders: polyarthritis.
• Infections and Infestations: superinfections, vaginitis.

Pregnancy and Lactation:

The use of this drug during pregnancy and breastfeeding is contraindicated.

Storage Conditions:

Store at a temperature not exceeding 30 °C.
Keep out of reach of children.

Packaging:

The cardboard box contains 2 blisters of 8 capsules each (16 capsules total) and a medical instruction insert.