Femoston 1/10 mg 28 tablets

Femoston 1/10 mg 28 tablets

Composition:

Each calendar pack contains:
14 tablets Estradiol 1 mg (as hemihydrate) - white tablets;
14 tablets Estradiol 1 mg (as hemihydrate) and Dydrogesterone 10 mg - gray tablets.

Description:

Femoston 1/10 is a continuous sequential hormone replacement therapy (HRT) for postmenopausal women. 
It combines estradiol a natural form of estrogen with dydrogesterone a synthetic progestogen to alleviate menopausal symptoms and prevent endometrial hyperplasia caused by estrogen alone.

Indications for use:

Treatment of estrogen deficiency symptoms in postmenopausal women.
Prevention of osteoporosis in postmenopausal women at high risk when other options are unsuitable.
Femoston 1/10 should be used in women with an intact uterus.

Dosage and administration:

One tablet daily continuously for 28 days.
Tablets should be swallowed whole with water at the same time each day.
A new pack is started the day after the previous one ends.
For initiation or continuation of HRT the lowest effective dose should be used for the shortest duration.
Which specific version of the medicine is suitable for a woman is decided by the doctor after a thorough check-up.

Contraindications:

• Known past or suspected breast cancer.
• Known or suspected estrogen-dependent malignant tumors e.g endometrial cancer.
• Undiagnosed vaginal bleeding.
• Untreated endometrial hyperplasia.
• History or presence of venous thromboembolism.
• Active or recent arterial thromboembolic disease e.g angina myocardial infarction.
• Acute liver disease or liver function abnormalities.
• Known hypersensitivity to active substances or excipients.
• Porphyria.

Precautions:

HRT should only be started for menopausal symptoms that significantly affect quality of life.
Periodic evaluation of benefits and risks is required.
Use caution in patients with history of estrogen-sensitive cancers thromboembolism liver disorders or endometriosis.
Patients should be monitored for signs of cardiovascular disease breast cancer and endometrial pathology.
HRT does not prevent dementia or cardiovascular disease.

Pregnancy and lactation:

Femoston is contraindicated during pregnancy and breastfeeding.
If pregnancy occurs treatment must be discontinued immediately.

Side effects:

Common side effects may include.
Headache breast pain tenderness abdominal pain nausea vaginal discharge menstrual-like bleeding
Uncommon or rare
Migraine mood changes rash weight change edema venous thromboembolism gallstones.

Storage conditions:

Store below 30°C
Keep out of reach of children
Store in the original packaging to protect from moisture and light.

Packaging:

Each carton contains one calendar pack with 28 film-coated tablets and a package insert.