E Mox 500 mg 16 capsules

E Mox 500 mg 16 capsules

Composition:

Amoxicillin (as trihydrate) 500 mg

Description:

E-MOX is a penicillin-group antibiotic used to treat bacterial infections of various localizations in adults and children.

Indications for Use:

E-MOX is used for the treatment of the following infections:

-Acute otitis media

-Acute bacterial sinusitis

-Acute streptococcal tonsillitis and pharyngitis

-Exacerbation of chronic bronchitis

-Community-acquired pneumonia

-Acute cystitis

-Asymptomatic bacteriuria in pregnant women

-Acute pyelonephritis

-Typhoid and paratyphoid fever

-Dental abscess with spreading infection

-Infections of prosthetic joints

-Eradication of Helicobacter pylori

-Lyme disease

-Endocarditis prophylaxis

Dosage and Administration:

The dosage of E-MOX depends on the type and severity of the infection, patient’s age, weight, and renal function.

Typical Dosages:

-Acute bacterial sinusitis: 250–500 mg every 8 hours or 750 mg – 1 g every 12 hours.

-Acute cystitis: 3 g twice daily for 1 day.

-Acute otitis media: 500 mg every 8 hours.

-Exacerbation of chronic bronchitis: 750 mg – 1 g every 8 hours for 10 days.

-Community-acquired pneumonia: 500 mg – 1 g every 8 hours.

-Lyme disease: 500 mg – 2 g every 8 hours, duration 10–30 days.

-Eradication of Helicobacter pylori: 750 mg – 1 g twice daily in combination with a proton pump inhibitor and another antibiotic (e.g., clarithromycin, metronidazole) for 7 days.

Dose adjustment is required in renal impairment. Detailed information is provided in the package insert.

Contraindications:

-Hypersensitivity to amoxicillin, penicillins, or other beta-lactam antibiotics

-History of severe allergic reactions (anaphylaxis, angioedema)

Precautions:

-Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS syndrome) may occur.

-High risk of allergic reactions in patients with penicillin hypersensitivity.

-Seizures may occur in renal failure, high doses, or predisposed patients (epilepsy, meningitis).

-Prolonged use may lead to the growth of resistant microorganisms and development of superinfections.

-Use may cause antibiotic-associated diarrhea, including pseudomembranous colitis.

Pregnancy and Lactation:

Pregnancy: Use only if the benefits outweigh the potential risks.

Lactation: Amoxicillin is excreted in breast milk and may cause diarrhea and fungal infections in the infant.

Side Effects:

Most common:

Diarrhea, nausea, skin rash.

Rare and very rare:

Leukopenia, thrombocytopenia, anemia.

Anaphylactic reactions, hypersensitivity.

Dizziness, hyperkinesia, seizures.

Hepatitis, elevated liver enzymes.

Pseudomembranous colitis, black hairy tongue.

Interstitial nephritis, crystalluria.

Storage Conditions:

Store in a dry place at temperatures not exceeding 25°C.

Packaging:

Carton box containing 2 blisters of 8 capsules and a package insert.