Debacolev 750 mg 10 tablets

Trade Name:

Debacolev

Composition:

Each tablet contains:

levofloxacin hemihydrate 768.67 mg,

which corresponds to the content of levofloxacin 750 mg.

Inactive ingredients:

hypromellose, crospovidone, microcrystalline cellulose, sodium stearyl fumarate.

Properties:

A synthetic broad-spectrum antibacterial drug from the group of fluoroquinolones containing levofloxacin, a levorotatory isomer of ofloxacin, as an active substance. Levofloxacin blocks DNA gyrase and topoisomerase IV, disrupts supercoiling and cross-linking of DNA breaks, inhibits DNA synthesis, and causes profound morphological changes in the cytoplasm, cell wall, and membranes of microbial cells.

Levofloxacin is active against most strains of microorganisms, both in vitro and in vivo.

Indications:

Treatment of infectious and inflammatory diseases caused by microorganisms sensitive to levofloxacin:

– community-acquired pneumonia;

-complicated urinary tract infections and pyelonephritis;

-chronic bacterial prostatitis;

– infections of the skin and soft tissues;

– for the complex treatment of drug-resistant forms of tuberculosis;

-prevention and treatment of anthrax in the airborne route of infection.

For the treatment of the following infectious and inflammatory diseases, levofloxacin can be used as an alternative to other antimicrobials:

– acute sinusitis;

– exacerbation of chronic bronchitis;

– uncomplicated cystitis.

Dosage and administration:

The drug is taken orally at 250 or 500 mg 1 or 2 times / day.Tablets should be swallowed without chewing and with a sufficient amount of liquid (from 0.5 to 1 cup).

The drug can be taken before meals or at any time between meals, because. Food intake does not affect the absorption of the drug.

On average, the course of treatment is 7-14 days, depending on the indications.

Contraindications:

-epilepsy;

-myasthenia gravis;

-tendon lesions associated with the use of fluoroquinolones in history;

-children and adolescents up to 18 years of age (due to the incomplete growth of the skeleton, since the risk of damage to cartilaginous growth zones cannot be completely excluded);

-pregnancy (it is impossible to completely exclude the risk of damage to the cartilaginous growth zones in the fetus);

– the period of breastfeeding (it is impossible to completely exclude the risk of damage to the cartilaginous growth zones of bones in a child);

-hypersensitivity to levofloxacin or other quinolones, as well as to any of the excipients of the drug.

Warnings and precautions:

The prevalence of acquired resistance in cultured strains of microorganisms may vary by geographic region and over time. In this regard, information on drug resistance in a particular country is required. For the treatment of severe infections or in case of treatment failure, a microbiological diagnosis should be established with the isolation of the pathogen and determination of its sensitivity to levofloxacin.

Side effects:

Nervous system: often – headache, dizziness; infrequently – drowsiness, tremor, dysgeusia (taste perversion); rarely – paresthesia, convulsions.

Mental disorders: often – insomnia; infrequently – a feeling of anxiety, confusion.

Digestive system: often – diarrhea, vomiting, nausea; infrequently – abdominal pain, dyspepsia, flatulence, constipation.

Liver and biliary tract: often – increased activity of ALT, AST, alkaline phosphatase, GGT.

Storage:

Store at a temperature not exceeding 30°C, in a dry place.

Package:

The carton box contains 2 blisters of 5 tablets, paper leaflet.