Recoxibright 90 mg 30 tablets

Recoxibright 90 mg 30 tablets

Compound:
Each tablet contains:
Etoricoxib 90 mg.
Auxiliary components:
Calcium hydrogen phosphate, Avicel, Aerosil, microcrystalline cellulose, sodium croscarmellose, magnesium stearate.
Properties:
Etoricoxib, when taken orally at therapeutic concentrations, is a selective inhibitor of cyclooxygenase-2 (COX-2). In clinical pharmacology studies, etoricoxib inhibited COX-2 in a dose-dependent manner with no effect on COX-1 at daily doses up to 150 mg.
Etoricoxib does not inhibit the synthesis of prostaglandins in the gastric mucosa and does not affect platelet function.
Indications:
- Treatment of chronic pain in the lower back;
- Symptomatic therapy of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, pain and inflammation associated with acute gouty arthritis;
- Short-term therapy of moderate and severe acute pain after dental surgery.
Dosage and administration:
The drug is taken orally, regardless of the meal, with a small amount of water.
The drug should be used in the minimum effective dose for the shortest possible course.
- The daily dose for osteoarthritis should not exceed 60 mg;
- The daily dose for rheumatoid arthritis should not exceed 90 mg;
- The daily dose for ankylosing spondylitis should not exceed 90 mg;
- The daily dose for chronic pain in the lower back should not exceed 60 mg;
- The maximum duration of treatment is limited to a period of 12 weeks;
- The daily dose for acute gouty arthritis should not exceed 120 mg, the maximum duration of treatment is limited to a period of 8 days;
- The daily dose for relief of pain after dental operations should not exceed 90 mg for a maximum of 3 days.
Contraindications:
Hypersensitivity to the active substance, any excipient of the drug;
- Active peptic ulcer or gastrointestinal bleeding; patients who have experienced bronchospasm, acute rhinitis, nasal polyps, angioedema, urticaria or other allergic reactions after the use of acetylsalicylic acid or NSAIDs, including COX-2 inhibitors;
- During pregnancy and breastfeeding;
- Severe liver dysfunction (plasma albumin <25 g/l or ≥10 points on the Child-Pugh scale);
- Renal creatinine clearance <30 ml/min;
- Children under the age of 16;
- Inflammatory bowel disease;
- Congestive heart failure (II–IV according to NYHA classification);
- Patients with hypertension, whose blood pressure is constantly higher than 140/90 mm Hg. Art. and not adequately controlled;
- Diagnosed ischemic heart disease, peripheral arterial disease and/or cerebrovascular disease.
Precautionary measures:
Caution is advised in the use of NSAIDs in the treatment of patients at increased risk of developing complications from the gastrointestinal tract: elderly patients, patients who use any other NSAID or acetylsalicylic acid at the same time, or patients with gastrointestinal diseases, namely ulcers and gastrointestinal bleeding in history.
Side effects:
Epigastric pain, nausea, vomiting, diarrhea, dyspepsia, flatulence, bloating, belching, increased peristalsis, constipation, dryness of the oral mucosa, gastritis, ulcer of the mucous membrane of the stomach or duodenum, irritable bowel syndrome, headache, dizziness, weakness, anaphylactic / anaphylactoid reactions, including a pronounced decrease in blood pressure and shock, palpitations, increased blood pressure.
Storage method:
Store at a temperature not exceeding 30 degrees.
Package:
The cardboard box contains 1, 2 or 3 blisters of 10 tablets, paper instructions.