Arcalion 200 mg 40 tablets

Tradename:

Arcalion

Arcalion

Compound:

Each tablet contains:

Sulbutiamine 200 mg

Auxiliary components:

Starch, anhydrous glucose, lactose monohydrate, magnesium stearate, talc, croscarmellose sodium, polysorbitol, povidone, sucrose, aerosil.

Properties:

Sulbutiamine is an original compound derived from thiamine through a series of structural modifications to the thiamine core:

– formation of a disulfide bond, the introduction of a lipophilic ester and the opening of a thiazole ring.

Thanks to this modification, sulbutiamine:

– we will well dissolve in fats that allows it to be quickly soaked up from a gastrointestinal tract and easily to get through BBB;

-capable of accumulating in cells of the reticular formation, hippocampus and dentate gyrus, as well as cells of Purkinje fibers and glomeruli of the granular layer of the cerebellar cortex, which is confirmed by histochemical analysis.

In placebo-controlled studies in humans, as well as in studies with active control, there was evidence of the effectiveness of the drug Arcalion in the symptomatic treatment of functional asthenia.

Sulbutiamine is metabolized to thiamine (vitamin B1). In complex with adenosine triphosphate (ATP), thiamine forms thiamine diphosphate (carboxylase or thiamine pyrophosphate), which takes part in carbohydrate metabolism as a coenzyme.

Indications:

Conditions of overwork in adults, accompanied by increased fatigue, decreased performance, weakness.

Mode of application:

inside. Only for adults.

Daily dose of the drug: 2-3 tablets (400-600 mg) in 2 doses (during breakfast and lunch):

1 tablet during breakfast and 1 tablet during lunch;

or 1 tablet during breakfast and 2 tablets during lunch;

Tablets should be swallowed whole with water.

The duration of treatment should not exceed 4 weeks.

Do not exceed the recommended dose and duration of the drug.

The patient should be warned that if the condition worsens or does not improve after 4 weeks, you should consult a doctor.

Contraindications:

-age up to 15 years (due to lack of clinical data);

-pregnancy;

– period of breastfeeding;

– lactose deficiency, galactosemia, glucose-galactose malabsorption syndrome, sucrase-isomaltase deficiency, fructose intolerance due to the content of glucose, lactose and sucrose in the preparation as excipients;

– hypersensitivity to the active substance (sulbutiamine) or any of the components of the drug.

Precautionary measures:

The excipients of the drug include glucose, lactose and sucrose. As a result, Arcalion is contraindicated for use in persons with lactase deficiency, galactosemia, glucose-galactose malabsorption syndrome, sucrase-isomaltase deficiency, fructose intolerance.

Side effects:

From the nervous system:

Tremor Headache Mental disorders Agitation

From the gastrointestinal tract:

Nausea Vomiting Abdominal pain Diarrhea

From the skin and subcutaneous tissues:

Rash Common disorders:

Malaise

Storage method:

Store at a temperature not exceeding 30 degrees.

Package:

The cardboard box contains 2 blisters of 20 tablets, paper instructions.