Enterogermina 4 Billion/5 ml oral suspension 10 vials

Enterogermina 4 Billion/5 ml oral suspension 10 Vials

Composition:
One 5 ml mini bottle contains:
Pores of polyantibiotic-resistant Bacillus clausii – 4 billion, purified water.
Properties:
Enterogermina is a preparation consisting of a suspension of Bacillus clausii spores, normal inhabitants of the intestine, with no pathogenic properties.
Administered orally, Bacillus clausii spores, due to their high resistance to both chemical and physical agents, cross the barrier of the acid gastric juices reaching, unharmed, the intestinal tract where they are transformed into metabolically active vegetative cells.
The administration of Enterogermina contributes to the recovery of the intestinal microbial flora altered during the course of intestinal microbial imbalance of diverse origin, due to the action of the Bacillus clausii.
Furthermore, since the Bacillus clausii is capable of producing various vitamins, in particular group B vitamins, it contributes to correcting the  dysvitaminosis caused by antibiotics and chemotherapeutic agents in general.
Enterogermina makes it possible to obtain a specific antigenic and antitoxic action, closely connected with the metabolic action of the B. clausii.
In addition, the high degree of heterologous resistance to the antibiotics, induced artificially, provides for the creation of the therapeutic basis for preventing the alteration of the intestinal microbial flora, following the selective action of antibiotics, especially the broad spectrum ones, or to re-establish its balance.
Indications:
Thanks to its concentration of only one vial per day Enterogermina 4 Billion is able to restore the alterations of the bacterial flora and is therefore suitable for the whole family (including infants) for the treatment of:
- Intestinal dysbiosis associated with antibiotic or chemotherapy treatments, often associated with gastrointestinal symptoms such as diarrhea, abdominal pain and increased air in the intestine
- Acute and chronic gastrointestinal disorders in infants, caused by intoxication and intestinal dysbiosis states
- Avitaminosis, i.e. states of vitamin deficiency due to imbalances in their production and assimilation in the intestine, given the ability of B. clausii to produce B vitamins.
Directions for use:
- Enterogermina 4 Billion can be taken during an antibiotic therapy and is able, during the treatment and in the following 7-10 days, to reduce the incidence of adverse ailments such as abdominal pain and diarrhea.
- There is no risk of developing antibiotic resistance, as the genes that give B. clausii the ability to resist antibiotics are not passed on to other bacteria.
- Enterogermina 4 Billion is odorless, tasteless and colorless. In addition, to facilitate its intake especially for children, it is possible to mix it with their favorite drinks, both cold and hot, such as milk, tea, fruit juices and herbal teas.
Adults: 1 vial per day.
Infants and children: 1 vial per day.
Side effects:
- Hypersensitivity reactions, including rash urticaria and angioedema;
- Bacteremia, septicemia or sepsis in immunocompromised patients or those hospitalized due to a serious illness.
Contraindications:
- Known hypersensitivity to the components of the product.
Warnings and precautions:
The possible presence of corpuscles visible in the mini bottles of Enterogermina® is due to aggregates of  Bacillus clausii spores and does not therefore indicate that the product has undergone any changes.
Shake the mini bottle before use.
This medicine is for oral use only. Do not inject or administer in any other way. •Severe anaphylactic reactions, such as anaphylactic shock, have occurred with incorrect route of administration.
There have been reports of bacteremia, septicemia or sepsis in patients taking Bacillus clausii who are  immunocompromised or are hospitalized due to a serious illness.
Enterogermina should be used in these patients only if the potential benefits outweigh the potential risks.
During antibiotic therapy, the product should be administered in the interval between one dose of antibiotic and the next.
There are no known medicinal interactions subsequent to the concomitant administration of other drugs.Because of antibiotic-resistance, Enterogermina can be administered in the interval between two doses of antibiotics. The antibiotic-resistance refers to: Penicillin, the Cephalosporins, Tetracyclines, Macrolides, Aminoglycosides, Novobiocin, Chloramphenicol, Thiamphenicol, Lincomycin, Isoniazid, Cycloserine, Rifampicin, Nalidixic acid and Pipemidic acid.
Enterogermina should be used during pregnancy only if the potential benefits to the mother outweigh the  potential risks, including those to the fetus.
Enterogermina should be used during breastfeeding only if the potential benefits to the mother outweigh the potential risks, including those to the breastfed child.
Effects on ability to drive and use machines:
The drug does not interfere with the ability to drive or use machinery.
Keep out of reach of children.
Storage:
Store at a temperature not exceeding 30°C
Package:
Carton box holds 10 vials of 5 ml for oral route.