Tradename:

Atacand

Atacand

Composition:

Each tablet contains:

Candesartan cilexetil – 4mg.

Auxiliary components: calcium carmellose, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, corn starch, macrogol.

Properties:

Atacand – is an angiotensin type 2 receptor antagonist and, therefore, an antihypertensive agent. Blocks type 1 angiotensin receptors, which leads to suppression of the effects of type 2 angiotensin (vasoconstrictor effect, stimulation of aldosterone synthesis and cell growth, regulation of water-salt metabolism). The antihypertensive effect is associated with a decrease in peripheral vascular resistance without an increase in the heart rate. The drug does not inhibit the angiotensin-converting enzyme. Does not affect other receptors or ion channels.

Indications:

arterial hypertension, heart failure (used as adjunctive therapy to ACE inhibitors, or in cases of intolerance).

Mode of application:

the drug should be taken orally, regardless of the meal once a day. In arterial hypertension, the initial and maintenance dose, regardless of age, is 8 mg per day, in some cases 16 mg. For persons with mild to moderate liver or kidney damage, the initial dose is 2 mg. The maximum antihypertensive effect is achieved within a month from the start of treatment. For heart failure, Atacand should be taken at 4 mg per day at the beginning of treatment, subsequently the dose can be doubled every 2 weeks (up to 32 mg per day). Atacand is effective when used simultaneously with other drugs for chronic heart failure – beta-blockers, ACE inhibitors, cardiac glycosides and diuretics. In old age and patients with impaired renal function, adjustment of the initial dose of the drug is not required.

Contraindications:

hypersensitivity to any component of the drug, pregnancy and lactation, children under 18 years of age, cholestasis, severe forms of li failure.

Precautions:

the drug can adversely affect kidney function. In case of renal failure, their performance should be regularly monitored. The use of Atacand can cause renal artery stenosis, hypotension (in the case of myocardial insufficiency). If surgery and the use of anesthetics are planned, the risk of hypotension should be considered. When a daily dose of 32 mg does not give the desired effect, consult with your doctor about the appropriateness of using the drug.

Side effects:

the drug is usually well tolerated. Frequent side effects – weakness, dizziness, headache, cough, rhinitis, pharyngitis, an increase in the frequency of respiratory infections, pain in the abdomen, back; edema, marked decrease in blood pressure, renal dysfunction, angioedema, hyperkalemia, hyponatremia, nausea, myalgia, urticaria, pruritus, rash.

Storage:

Store at a temperature not exceeding 30C, of reach of children.