Ioprost 50 mcg

Trade Name:

Ioprost

Composition:

Each ml of solution contains:

latanoprost 50 mcg

Inactive ingredients:

sodium chloride, sodium dihydrogen phosphate, sodium hydrogen phosphate, benzalkonium chloride, purified water.

Properties:

Antiglaucoma drug, prostaglandin F2α analogue and selective FP receptor agonist. Reduces intraocular pressure by increasing the outflow of aqueous humor, mainly along the uveoscleral pathway. It does not have a significant effect on the production of aqueous humor and does not affect the hematoophthalmic barrier.

The decrease in intraocular pressure begins 3-4 hours after the administration of the drug, the maximum effect is after 8-12 hours, the effect lasts for at least 24 hours.

Indications:

– open-angle glaucoma;

-increased intraocular pressure.

Dosage and administration:

In the conjunctival sac of the affected eye, 1 drop is instilled 1 time / day, in the evening.

If a dose is missed, the next dose is administered as usual (i.e., the dose is not doubled).

Contraindications:

-children and adolescents up to 18 years;

– Hypersensitivity to the components of the drug.

The drug should be used with caution in patients with aphakia, pseudo-aphakia with rupture of the posterior lens capsule, in patients with known risk factors for macular edema (during the treatment with latanoprost, cases of macular edema, including cystoid edema, have been described); inflammatory, neovascular or congenital glaucoma (due to lack of sufficient experience with the drug).

Warnings and precautions:

Causes a gradual change in eye color by increasing the amount of brown pigment in the iris.This effect occurs predominantly in patients with mixed iris coloration, such as blue-brown, grey-brown, green-brown, or yellow-brown, due to an increase in melanin content in iris stromal melanocytes. Usually brown pigmentation extends concentrically around the pupil to the periphery of the iris, while the entire iris or parts of it may become more intense brown. In the case of an intense change in eye pigmentation, therapy is stopped.

The drug contains benzalkonium chloride, which can be absorbed by contact lenses. Before instillation of eye drops, contact lenses should be removed; lenses can be inserted only 15 minutes after instillation.

Side effects:

On the part of the organ of vision: eye irritation (burning sensation, feeling of sand in the eyes, itching, tingling and sensation of a foreign body), blepharitis, conjunctival hyperemia, eye pain, increased pigmentation of the iris, transient punctate erosion of the epithelium, swelling of the eyelids, swelling and erosion of the cornea , conjunctivitis, elongation, thickening, an increase in the number and increased pigmentation of eyelashes and vellus hair, iritis / uveitis, keratitis, macular edema (including cystoid), a change in the direction of eyelash growth, sometimes causing eye irritation, blurred vision.

Dermatological reactions: rash, darkening of the skin of the eyelids and local skin reactions from the eyelids.

From the nervous system: dizziness, headache.

On the part of the respiratory system: bronchial asthma (including acute attacks or exacerbation of the disease in patients with a history of bronchial asthma), shortness of breath.From the musculoskeletal system: muscle pain, joint pain.

Other: nonspecific chest pain.

Storage:

Store at a temperature not exceeding 30°C.

After opening, the shelf life of the drug is 1 month.

Package:

The carton box contains a 3 ml dropper bottle and paper leaflet.