Forxiga 10 mg 28 tablets

Forxiga 10 mg 28 tablets

Composition:
Dapagliflozin 10 mg.
Excipients:
microcrystalline cellulose, anhydrous lactose, crospovidone, silicon dioxide, magnesium stearate.
Description:
Forxiga (dapagliflozin) is a selective, reversible inhibitor of sodium-glucose co-transporter 2 (SGLT2). It reduces glucose and sodium reabsorption in renal tubules, increases urinary glucose excretion, and provides an osmotic diuretic effect. Secondary benefits include reduction of intraglomerular pressure, moderate decrease in blood pressure and body weight, and an increase in hematocrit.
Properties:
Improves glycemic control in type 2 diabetes
Reduces risk of hospitalization for heart failure
Additional effects: moderate weight loss, blood pressure reduction, increased hematocrit
Indications:
   Type 2 diabetes mellitus in adults:
 As monotherapy when metformin is not tolerated
 In combination therapy with metformin, sulfonylureas, or thiazolidinediones
 As initial combination with metformin when appropriate
   Type 2 diabetes with established cardiovascular disease or ≥2 risk factors to reduce risk of hospitalization for heart failureChronic heart failure in adults
Dosage:
Take orally, once daily, with or without food. Swallow tablet whole with water.
T2DM: 10 mg once daily (monotherapy or combination therapy)
Heart failure: 10 mg once daily
Contraindications:
Hypersensitivity to any component
Type 1 diabetes, diabetic ketoacidosis
Severe renal impairment (eGFR <30 ml/min/1.73 m²), end-stage renal disease, dialysis
Lactose intolerance
Pregnancy and breastfeeding
Children and adolescents under 18 years
Precautions:
Limited experience in patients with severe renal impairment or on dialysis
Requires monitoring during long-term treatment
Adverse effects:
Infections: vulvovaginitis, balanitis, urinary tract infections
Metabolism: hypoglycemia (with sulfonylureas or insulin)
Nervous system: dizziness
Skin: rash
Musculoskeletal: back pain
Urinary system: dysuria, polyuria
Storage conditions:
Store below 30 °C in a dry place.
Packaging:
Carton box, 28 tablets (2 blisters × 14 tablets + leaflet).