Depram 40 mg, 20 tablets

Trade Name:

Depram 40 mg

20 film coated tablets 

Composition:

Citalopram hydrobromide 40 mg

Properties:

This medication is used to treat depression . Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

Indications:

This antidepressant is useful in the treatment of obsessive-compulsive disorder, social phobia, panic disorder, generalized anxiety disorder (GAD), and post-traumatic stress disorder (PTSD). It may be indicated for pain, insomnia, and migraine as well.

Dosage and administration:

It usually takes around 7 days before you begin to notice the effects of antidepressants. Contact your doctor if you have not noticed any improvement after 4 weeks, as they may recommend increasing your dose or trying a different antidepressant. It's usually recommended that a course of antidepressants lasts at least 6 months, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely. The recommended course of treatment largely depends on weighing up the benefits of the medicine against the side effects. If your illness is severe and the medicine is effective, treatment will often be continued. If your illness is mild and the medicine does not help and causes side effects, continued treatment will not be recommended.

-Hepatic impairment: According to product labeling, the dosage needs to be reduced to 20 mg daily for patients with hepatic impairment.

-Renal impairment: No dose adjustment is necessary for patients with mild-to-moderate renal impairment. Patients with severe renal impairments should be closely monitored for possible adverse reactions.

Side effects:

Nausea, increased appetite and weight gain, loss of sexual desire and other sexual problems, such as erectile dysfunction and decreased orgasm, fatigue and drowsiness, insomnia, dry mouth, blurred vision, constipation, dizziness, agitation, irritability, anxiety

Contraindications:

-Patients with severe renal impairments should be closely monitored for possible adverse reactions. 

-Pregnancy considerations: Citalopram is an FDA pregnancy category C drug. Citalopram is not an absolute contraindication in pregnancy but is not generally recommended, especially during the first trimester.

Warnings and precautions:

• Some products that may interact with this drug are: other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, “blood thinners” such as dabigatran/warfarin). Aspirin can increase the risk of bleeding when used with this medication.
• Pregnancy and lactation:

Both psychiatric experts and ob-gyn experts agree that if you have mild depression and have been symptom-free for at least six months, you may be able to stop using antidepressants under a doctor’s supervision before getting pregnant or while you are pregnant. Psychotherapy, along with lifestyle measures, may be all that you need to manage your depression. You may be able to get through your pregnancy without antidepressants if you: 

-Talk with a therapist on a regular basis -Exercise more 

-Spend time outside 

-Practice yoga and meditation 

-Minimize your stress 

But, the experts point out, it will be better for both you and your baby to stay on antidepressants while pregnant if any of the following is true: 

-You have a history of severe or recurrent depression;

-You have a history of other mental illnesses, such as bipolar disorder;

-You have ever been suicidal.

Storage:

Store at a room temperature 20°C to 25°C

Package:

Carton box holds 2 strips each of 10 film coated tablets and paper instructions