Blockium Diu 100/25mg 15 tablets

Tradename:

blockium diu

Blokium diu

Compound:

Each tablet contains:

Atenolol 100 mg

Chlortalidone 25 mg

Auxiliary components:

corn starch povidone (polyvinylpyrrolidone), sodium lauryl sulfate, talc, colloidal silicon dioxide, magnesium stearate.

Properties:

Combined antihypertensive drug, has a long-term hypotensive effect. The effect is due to the action of two components: a beta1-blocker (atenolol) and a diuretic (chlorthalidone).

Atenolol is a cardioselective beta1-blocker. Selectivity decreases with increasing dose. Atenol does not have intrinsic sympathomimetic and membrane stabilizing effects. Like other beta-blockers, it has a negative inotropic effect, slows down heart rate.

Chlorthalidone is a non-thiazide sulfonamide diuretic that enhances the excretion of sodium and chlorine. Increases excretion of potassium, magnesium and bicarbonate. The mechanism of antihypertensive action is probably related to sodium excretion. The combination of atenolol with diuretics is more effective than the use of each of the components separately.

The effect of the drug persists for 24 hours after a single oral dose in a daily dose.

Indications:

Arterial hypertension.

Dosage and administration:

The average dose of Blokium diu for adults is 1 tablet per day.

As a rule, the use of the drug at a dose corresponding to 100 mg of atenolol gives a good clinical effect. A subsequent increase in dose either does not lead to a further decrease in blood pressure, or reduces it very slightly. If necessary, an additional antihypertensive agent may be prescribed.

Contraindications:

– severe bradycardia;

– cardiogenic shock;

– severe arterial hypotension;

– metabolic acidosis;

– severe disorders of peripheral circulation;

-AV-blockade II and III degree;

-SSSU;

– untreated pheochromocytoma;

– acute heart failure;

– chronic heart failure;

– vasospastic angina (Prinzmetal’s angina);

-bronchial asthma;

-obstructive bronchitis;

-diabetes;

-hypoglycemia;

-gout;

– myasthenia gravis;

– acute hepatitis;

– acute renal failure;

-children and adolescents up to 18 years;

– Hypersensitivity to the components of the drug.

Precautionary measures:

It should be borne in mind that the use of the drug may mask the phenomena of thyrotoxicosis and hypoglycemia.

With the development against the background of the use of the drug bradycardia (heart rate up to 50 bpm) with clinical symptoms, the dose should be reduced or the drug should be discontinued.

Side effects:

From the side of the cardiovascular system: bradycardia, increased symptoms of heart failure, orthostatic hypotension (may be accompanied by fainting), cold extremities. Perhaps the appearance of arrhythmias, AV blockade, a symptom of intermittent claudication, Raynaud’s syndrome.

From the side of the central nervous system and peripheral nervous system: confusion, dizziness, headache.

From the digestive system: dry mouth, gastrointestinal disorders.

From the hemopoietic system: leukopenia, purpura, thrombocytopenia, agranulocytosis, eosinophilia.

Dermatological reactions: alopecia, dry eyes, psoriasis-like reactions, exacerbation of psoriasis, skin rash, photosensitivity.

From the respiratory system: bronchospasm (in patients with bronchial asthma or with a history of bronchospasm).

Storage method:

Store at a temperature not exceeding 30 degrees.

Package:

The cardboard box contains a blister of 15 tablets, paper instructions.