Fam 10 mg 20 tablets

Tradename:

Fam (Fam)

Compound:

Each tablet contains:

Ketorolac tromethamine 10 mg

Auxiliary components:

Starch, magnesium stearate, talc, aerosil.

Properties:

Ketorolac – NSAIDs, has a pronounced analgesic (pain-relieving) effect, also has an anti-inflammatory and moderate antipyretic effect.

The mechanism of action is associated with non-selective inhibition of the activity of COX-1 and COX-2 enzymes, mainly in peripheral tissues, resulting in inhibition of the biosynthesis of prostaglandins – modulators of pain sensitivity, inflammation and thermoregulation. Ketorolac is a racemic mixture of R(+) and S(-)-enantiomers, while the analgesic (pain-relieving) effect is due to the S(-)-enantiomer.

Ketorolac does not affect opioid receptors, does not depress breathing, does not cause drug dependence, does not have a sedative and anxiolytic effect.

The strength of the analgesic (pain-relieving) effect is comparable to morphine, significantly superior to other NSAIDs.

After oral administration, the onset of analgesic (pain-relieving) action is observed after 1 hour, respectively, the maximum effect is achieved after 2-3 hours.

Indications:

– pain syndrome of strong and moderate severity: injuries, toothache, pain in the postoperative period, cancer, myalgia, arthralgia, neuralgia, sciatica, dislocations, sprains, rheumatic diseases.

It is intended for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease.

Dosage and administration:

The drug should be used orally once or repeatedly, depending on the severity of the pain syndrome.

A single dose is 10 mg, with repeated administration it is recommended to take 10 mg up to 4 times / day, depending on the severity of pain. The maximum daily dose should not exceed 40 mg.

When taken orally, the duration of the course should not exceed 5 days.

Contraindications:

– complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including history);

– urticaria, rhinitis caused by taking NSAIDs (in history);

– intolerance to drugs of the pyrazolone series;

– dehydration, hypovolemia (regardless of the cause that caused it);

-bleeding or high risk of their development;

– condition after coronary artery bypass grafting;

– confirmed hyperkalemia;

– inflammatory bowel disease;

– erosive and ulcerative lesions of the gastrointestinal tract in the acute stage, peptic ulcers;

-hypocoagulation (including hemophilia);

– severe renal failure (CC less than 30 ml / min);

– severe liver failure or active liver disease;

– hemorrhagic stroke (confirmed or suspected);

– hemorrhagic diathesis;

– violation of hematopoiesis;

-pregnancy;

– childbirth;

– lactation period (breastfeeding);

-children under 16 years of age (efficacy and safety have not been established);

– hypersensitivity to ketorolac and other NSAIDs.

Precautionary measures:

When combined with other NSAIDs, fluid retention, cardiac decompensation, and arterial hypertension may occur.

To reduce the risk of developing NSAID-gastropathy, antacids, misoprostol, omeprazole are prescribed.

Side effects:

From the digestive system: often (especially in elderly patients over 65 years of age with a history of erosive and ulcerative lesions of the gastrointestinal tract) – gastralgia, diarrhea.

From the side of the central nervous system and peripheral nervous system: often – headache, dizziness, drowsiness.

Other: often – edema (including face, shins, ankles, fingers, feet), weight gain; less often – excessive sweating; rarely – swelling of the tongue, fever.

Storage method:

Store at a temperature not exceeding 30 degrees.

Package:

Cardboard box contains 2 blisters of 10 tablets and paper instructions.